American Express Co., bracing for a decline in profit after the loss of a key retail partner, made a series of organizational changes including combining U.S. and international units and said that consumer product head Josh Silverman is leaving the firm.

Doug Buckminster, who had led international card operations, was named president of a newly unified global consumer unit, while Anre Williams will oversee a combined merchant services and loyalty business, New York-based Amex said Wednesday in a statement. Steve Squeri, who was named vice chairman earlier this year, will be in charge of corporate and small business initiatives globally as well as merchant financing and the foreign-exchange payments business, the firm said. Silverman is leaving to join Greylock Partners as an executive-in-residence.

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